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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1787318Generated: October 30, 2026

N-(3-(4-Formylphenyl)-4,6,7-trimethyl-2,3-dihydro-1-benzofuran-5-yl)-3,3-dimethylbutanamide → N-(3-(4-(1-Hydroxyethyl)phenyl)-4,6,7-trimethyl-2,3-dihydro-1-benzofuran-5-yl)-3,3-dimethylbutanamide

https://huagongshe.com/reaction/1787318

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-(3-(4-Formylphenyl)-4,6,7-trimethyl-2,3-dihydro-1-benzofuran-5-yl)-3,3-dimethylbutanamideHCID 23113872—
ReactantHCID 178418573HCID 178418573—
ProductN-(3-(4-(1-Hydroxyethyl)phenyl)-4,6,7-trimethyl-2,3-dihydro-1-benzofuran-5-yl)-3,3-dimethylbutanamideHCID 2311406693%

Reaction Steps

Using N-(3-(4-formylphenyl)-4,6,7-trimethyl-2,3-dihydro-1-benzofuran-5-yl)-3,3-dimethylbutanamide obtained in Example 174 and methylmagnesium bromide, the title compound was synthesized in the same manner as Example 22.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07507841B2
Source datasetuspto-grants-2009_03
ORD IDord-dfdbbe330fc644a7a4539b79d81db0d7
Source noteuspto-grants-2009_03