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HRID1787427

反应详情

EQUATION

反应方程式

HRID 1787427 的结构方程式

REACTANTS

反应物

2
结构：CC(C)(C)NS(=O)(=O)c1cccc(B(O)O)c1
HCID44119538

[3-(tert-Butylsulfamoyl)phenyl]boronic acid

C10H16BNO4S

结构：O=C1CC(c2cccc(Br)c2)=Nc2ccc(C(F)(F)F)cc2N1
HCID67361818

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)(C)NS(=O)(=O)c1cccc(-c2cccc(C3=Nc4ccc(C(F)(F)F)cc4NC(=O)C3)c2)c1
HCID25050017

未命名化合物

PROCEDURE

实验过程

The title compound was prepared from 4-(3-bromo-phenyl)-8-trifluoromethyl-1,3-dihydro-benzo[b][1,4]diazepin-2-one (Example B.2) (200 mg, 0.50 mmol) and commercially available 3-tert-butylsulfamoyl-benzeneboronic acid [CAS-no. 221290-14-8] (161 mg, 0.60 mmol) according to the general procedure II. Obtained as an off-white solid (31 mg, 12%). MS (ISP) 515.9 [(M+H)+]; mp 179-181° C.