4-Fluorobenzylamine → HCID 40111420, compound

HRID 1787463Notes

Reaction equation

HRID 1787463 reaction equation
[F:1][C:2]1[CH:9]=[CH:8][C:5]([CH2:6][NH2:7])=[CH:4][CH:3]=1.[Cl:10][C:11]1[CH:16]=[N:15][CH:14]=[C:13](Cl)[N:12]=1>>[Cl:10][C:11]1[N:12]=[C:13]([NH:7][CH2:6][C:5]2[CH:8]=[CH:9][C:2]([F:1])=[CH:3][CH:4]=2)[CH:14]=[N:15][CH:16]=1

Participants

3

Reactant 2

HCID 673264-FluorobenzylamineHCID 785042,6-Dichloropyrazine

Product 1

HCID 40111420HCID 40111420, compoundYield 99%

Procedure

In a procedure analogous to example 1, reaction of 4-fluorobenzylamine (3.75 g, 30.0 mmol) and 2,6-dichloropyrazine (1.49 g, 10.0 mmol) furnished the product (2.35 g, 99%).

Sources & evidence

ORD record
ord-9a663d1d84b441e08f3b7c509ebfb0a1
Source dataset
uspto-grants-2009_03
Patent number
US07511047B2

Reaction notes

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