HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methylimidazole → 6-(2-Methyl-1H-imidazol-1-yl)-N-[(1R)-1-phenylethyl]pyrazin-2-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methylimidazole | HCID 12749 | — |
| Reactant | 6-chloro-N-[(1R)-1-phenylethyl]pyrazin-2-amine | HCID 58717082 | — |
| Product | 6-(2-Methyl-1H-imidazol-1-yl)-N-[(1R)-1-phenylethyl]pyrazin-2-amine | HCID 10468835 | 96.2% |
Reaction Steps
In a procedure analogous to example 2, reaction of 6-chloro-N-[(1R)-1-phenylethyl]pyrazin-2-amine (150 mg, 0.64 mmol) and 2-methylimidazole (58 mg, 0.71 mmol) furnished the product (172 mg, 40%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07511047B2 |
| Source dataset | uspto-grants-2009_03 |
| ORD ID | ord-fbf04f7c536d4d9c8ddd59cb76533542 |
| Source note | uspto-grants-2009_03 |