Benzylamine → N-Benzyl-6-chloropyrazin-2-amine

HRID 1787469Notes

Reaction equation

HRID 1787469 reaction equation
[CH2:1]([NH2:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[Cl:9][C:10]1[CH:15]=[N:14][CH:13]=[C:12](Cl)[N:11]=1>>[CH2:1]([NH:8][C:12]1[CH:13]=[N:14][CH:15]=[C:10]([Cl:9])[N:11]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 7504BenzylamineHCID 785042,6-Dichloropyrazine

Product 1

HCID 11708350N-Benzyl-6-chloropyrazin-2-amineYield 98%

Procedure

In a procedure analogous to example 1, reaction of benzylamine (3.21 g, 30.0 mmol) and 2,6-dichloropyrazine (1.49 g, 10.0 mmol) furnished the product ( 2.15 g, 98%).

Sources & evidence

ORD record
ord-bb875c97398041bcaf5318ad6eb874f9
Source dataset
uspto-grants-2009_03
Patent number
US07511047B2

Reaction notes

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