HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzimidazole → 6-(1H-Benzimidazol-1-yl)-N-[(1R)-1-phenylethyl]pyrazin-2-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzimidazole | HCID 5798 | — |
| Reactant | 6-chloro-N-[(1R)-1-phenylethyl]pyrazin-2-amine | HCID 58717082 | — |
| Product | 6-(1H-Benzimidazol-1-yl)-N-[(1R)-1-phenylethyl]pyrazin-2-amine | HCID 10245172 | 59% |
Reaction Steps
In a procedure analogous to example 12, reaction of 6-chloro-N-[(1R)-1-phenylethyl]pyrazin-2-amine (240 mg, 1.03 mmol) and benzimidazole (130 mg, 1.10 mmol) furnished the product (187 mg, 59%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07511047B2 |
| Source dataset | uspto-grants-2009_03 |
| ORD ID | ord-6d5162d9b572409aacca0f874c4f9785 |
| Source note | uspto-grants-2009_03 |