HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzimidazole → 6-(1H-Benzimidazol-1-yl)-N-[(1S)-1-phenylethyl]pyrazin-2-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzimidazole | HCID 5798 | — |
| Reactant | 6-Chloro-N-[(1S)-1-phenylethyl]pyrazin-2-amine | HCID 58717080 | — |
| Product | 6-(1H-Benzimidazol-1-yl)-N-[(1S)-1-phenylethyl]pyrazin-2-amine | HCID 10087054 | 38% |
Reaction Steps
In a procedure analogous to example 12, reaction of 6-chloro-N-[(1S)-1-phenylethyl]pyrazin-2-amine (140 mg, 0.60 mmol) and benzimidazole (78 mg, 0.66 mmol) furnished the product (71 mg, 38%):
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07511047B2 |
| Source dataset | uspto-grants-2009_03 |
| ORD ID | ord-1d965640d7554ac59037e3ef714c2090 |
| Source note | uspto-grants-2009_03 |