Hydrazine, ethyl-, ethanedioate (1:1) → Ethanol

Participants

Reaction Conditions

Reaction Steps

A mixture of ethylbenzoylisoxazole-3-carboxylate (G. Renzi, V. Dal Piaz et al. Gazz. Chim. Ital., 1968, 98, 656) (0.25 g, 1.02 mmol) and polyphosphoric acid (2.5 g) was gently warmed at 50° C. until the solution became clear. Ethylhydrazine oxalate (0.5 g, 3.33 mmol) was added and the mixture was warmed at 90° C. for 5 hours. After cooling, ice-cold water was added and the precipitate was collected by filtration. The final product was purified by recrystallization from ethanol (0.24 g, 93% yield)

Provenance & Evidence