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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1787567Generated: October 30, 2026

Hydrochloric Acid → HCID 66594108, compound

https://huagongshe.com/reaction/1787567

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 57599804HCID 57599804—
SolventMethanolHCID 887—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 66594108HCID 6659410889%

Reaction Steps

To a solution of N-imidazo[1,2-c]quinazolin-5-ylnicotinamide (40 mg, 0.14 mmol) in methanol (20 ml) was added a 4N solution of HCl in 1,4dioxane (0.5 ml). The mixture was concentrated under reduced pressure. The resulting solid was collected by filtration, washed with tetrahydrofurane and dried under reduced pressure to give N-imidazo[1,2-c]quinazolin-5-ylnicotinamide hydrochloride (40 mg, 89% yield) as a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07511041B2
Source datasetuspto-grants-2009_03
ORD IDord-78514312fa364253bc66280673ba10bb
Source noteuspto-grants-2009_03