1-(Benzenesulfonyl)-3-iodo-1H-pyrrolo[2,3-b]pyridine → HCID 57600363, compound

HRID 1787582Notes

Reaction equation

HRID 1787582 reaction equation
[C:1]1([S:7]([N:10]2[C:14]3=[N:15][CH:16]=[CH:17][CH:18]=[C:13]3[C:12](I)=[CH:11]2)(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[N:20]1[CH:25]=[CH:24][CH:23]=[CH:22][C:21]=1[C:26]1[C:27](B(O)O)=[C:28]2[CH2:33][CH2:32][CH2:31][N:29]2[N:30]=1>>[C:1]1([S:7]([N:10]2[C:14]3=[N:15][CH:16]=[CH:17][CH:18]=[C:13]3[C:12]([C:27]3[C:26]([C:21]4[CH:22]=[CH:23][CH:24]=[CH:25][N:20]=4)=[N:30][N:29]4[CH2:31][CH2:32][CH2:33][C:28]=34)=[CH:11]2)(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 242292281-(Benzenesulfonyl)-3-iodo-1H-pyrrolo[2,3-b]pyridineHCID 59710031(2-pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole-3-boronic acid

Product 1

HCID 57600363HCID 57600363, compound

Procedure

Using Preparation 3A, 1-benzene-sulfonyl-3-iodo-1H-pyrrolo[2,3-b]pyridine (Preparation 5) is reacted with 2-(pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole-3-boronic acid (Preparation 2) to provide the titled product. MS (ES) m/z=442 (M+H).

Sources & evidence

ORD record
ord-85b8133d19774a839e866e15eabf782d
Source dataset
uspto-grants-2009_03
Patent number
US07511056B2

Reaction notes

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