2-Bromo-5-methylpyridine → HCID 16118698, compound
Reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([C:7]2[CH:16]=[N:15][C:14]([NH2:17])=[C:13]3[C:8]=2[CH:9]=[CH:10][CH:11]=[N:12]3)[CH:2]=1.Br[C:19]1[CH:24]=[CH:23][C:22]([CH3:25])=[CH:21][N:20]=1>>[CH3:25][C:22]1[CH:23]=[CH:24][C:19]([NH:17][C:14]2[N:15]=[CH:16][C:7]([C:3]3[CH:2]=[N:1][CH:6]=[CH:5][CH:4]=3)=[C:8]3[C:13]=2[N:12]=[CH:11][CH:10]=[CH:9]3)=[N:20][CH:21]=1Participants
3
Procedure
The title compound, MS: m/e=314.0 (M+H+), was prepared in accordance with the general method of example 6 step 3 from 5-pyridin-3-yl-[1,7]naphthyridin-8-ylamine and 2-bromo-5-methylpyridine.
Sources & evidence
- ORD record
- ord-85cac396e4e94f9086f5e652b8e1564b
- Source dataset
- uspto-grants-2009_03
- Patent number
- US07511055B2
Reaction notes
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