2-Bromo-5-chloropyridine → HCID 57600347, compound

HRID 1787597Notes

Reaction equation

HRID 1787597 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([C:8]2[CH:17]=[N:16][C:15]([NH2:18])=[C:14]3[C:9]=2[CH:10]=[CH:11][CH:12]=[N:13]3)[CH:5]=[N:6][CH:7]=1.Br[C:20]1[CH:25]=[CH:24][C:23]([Cl:26])=[CH:22][N:21]=1>>[Cl:26][C:23]1[CH:24]=[CH:25][C:20]([NH:18][C:15]2[N:16]=[CH:17][C:8]([C:4]3[CH:5]=[N:6][CH:7]=[C:2]([F:1])[CH:3]=3)=[C:9]3[C:14]=2[N:13]=[CH:12][CH:11]=[CH:10]3)=[N:21][CH:22]=1

Participants

3

Reactant 2

HCID 8170982-Bromo-5-chloropyridineHCID 68621638HCID 68621638, compound

Product 1

HCID 57600347HCID 57600347, compound

Procedure

The title compound, MS: m/e=352.1 (M+H+), was prepared in accordance with the general method of example 15 step 3 from 5-(5-fluoro-pyridin-3-yl)-[1,7]naphthyridin-8-ylamine and 2-bromo-5-chloropyridine.

Sources & evidence

ORD record
ord-18a9897268bd4a6ab6f168318dcee386
Source dataset
uspto-grants-2009_03
Patent number
US07511055B2

Reaction notes

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