1-Methyl-3-aminopyrazole → (2-Methyl-[1,7]naphthyridin-8-yl)-(1-methyl-1H-pyrazol-3-yl)-amine

HRID 1787603Notes

Reaction equation

HRID 1787603 reaction equation
Cl[C:2]1[N:3]=[CH:4][CH:5]=[C:6]2[C:11]=1[N:10]=[C:9]([CH3:12])[CH:8]=[CH:7]2.[CH3:13][N:14]1[CH:18]=[CH:17][C:16]([NH2:19])=[N:15]1>>[CH3:12][C:9]1[CH:8]=[CH:7][C:6]2[C:11](=[C:2]([NH:19][C:16]3[CH:17]=[CH:18][N:14]([CH3:13])[N:15]=3)[N:3]=[CH:4][CH:5]=2)[N:10]=1

Participants

3

Reactant 2

HCID 1372541-Methyl-3-aminopyrazoleHCID 576003498-Chloro-2-methyl-1,7-naphthyridine

Product 1

HCID 16118556(2-Methyl-[1,7]naphthyridin-8-yl)-(1-methyl-1H-pyrazol-3-yl)-amine

Procedure

The title compound, MS: m/e=240.3 (M+H+), was prepared in accordance with the general method of example 1 from 8-chloro-2-methyl-[1,7]naphthyridine (Example E) and 1-methyl-1H-pyrazol-3-ylamine.

Sources & evidence

ORD record
ord-f633ee4799454ad18ca22b3f5fdb2bc8
Source dataset
uspto-grants-2009_03
Patent number
US07511055B2

Reaction notes

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