HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Thiazolamine, 4-(trifluoromethyl)- → HCID 16117056, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Thiazolamine, 4-(trifluoromethyl)- | HCID 1201417 | — |
| Reactant | (Pyrimidin-5-yl)boronic acid | HCID 2795193 | — |
| Reactant | 8-Chloro-5-iodo-2-methyl-[1,7]naphthyridine | HCID 57600352 | — |
| Product | HCID 16117056 | HCID 16117056 | — |
Reaction Steps
The title compound, MS: m/e=389.2 (M+H+), was prepared in accordance with the general method of example 15 step 1 and step 3 from 8-chloro-5-iodo-2-methyl-[1,7]naphthyridine (Example I), 5-pyrimidineboronic acid and 2-amino-4-(trifluoromethyl)thiazole.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07511055B2 |
| Source dataset | uspto-grants-2009_03 |
| ORD ID | ord-b73d9c8c08aa4d90ab4f6fb64d5e25b7 |
| Source note | uspto-grants-2009_03 |