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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1787640Generated: October 28, 2026

1,3-Dimethylpyrazole-5-boronic acid → HCID 16117182, compound

https://huagongshe.com/reaction/1787640

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,3-Dimethylpyrazole-5-boronic acidHCID 11252054—
Reactant2-Methyl-1,3-thiazol-4-amineHCID 14772700—
Reactant8-Chloro-5-iodo-2-methyl-[1,7]naphthyridineHCID 57600352—
ProductHCID 16117182HCID 16117182—

Reaction Steps

The title compound, MS: m/e=351.2 (M+H+), was prepared in accordance with the general method of example 15 step 1 and step 3 from 8-chloro-5-iodo-2-methyl-[1,7]naphthyridine (Example I), 1,3-dimethyl-1H-pyrazole-5-boronic acid (Example J) and 4-amino-2-methylthiazole (Example F).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07511055B2
Source datasetuspto-grants-2009_03
ORD IDord-8c6e12f66ffa48a48b47d319f6b6d44a
Source noteuspto-grants-2009_03