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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1787653Generated: October 30, 2026

2-Methyl-1,3-thiazol-4-amine → HCID 16117318, compound

https://huagongshe.com/reaction/1787653

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-1,3-thiazol-4-amineHCID 14772700—
Reactant(5-Fluoropyridin-3-yl)boronic acidHCID 44717403—
Reactant8-Chloro-5-iodo-2-methyl-[1,7]naphthyridineHCID 57600352—
ProductHCID 16117318HCID 16117318—

Reaction Steps

The title compound, MS: m/e=352.2 (M+H+), was prepared in accordance with the general method of example 15 step 1 and step 3 from 8-chloro-5-iodo-2-methyl-[1,7]naphthyridine (Example I), 3-fluoropyridine-5-boronic acid and 4-amino-2-methylthiazole (Example F).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07511055B2
Source datasetuspto-grants-2009_03
ORD IDord-66faef90f8194b22aa7973d76b8e5556
Source noteuspto-grants-2009_03