反应详情

温度

100 °C

The mixture of 8-cyclobutyl-3-pentyl-2-thioxo-1,2,3,7-tetrahydro-6H-purin-6-one (0.6 g, 2.0 mmol) in 20 M of hydrazine in water (20 mL) was stirred at 100° C. overnight. After cooling to room temperature, the solid formed was filtered and dried Cooled down, the solid was isolated to give yield the desired product (230 mg, 38.6%). LCMS calculated for C14H23N6O(M+H): 291.2; found: 291.2.

1. temperatureAfter cooling to room temperature
2. customthe solid formed
3. filtrationwas filtered
4. customdried
5. temperatureCooled down
6. customthe solid was isolated
7. customto give