反应详情

The mixture of N′-[(2E)-6-oxo-3-pentyl-1,3,6,7-tetrahydro-2H-purin-2-ylidene]-3-(5-phenyl-1,3,4-oxadiazol-2-yl)propanohydrazide (485 mg, 1.11 mmol) in toluene (50 mL) was heated to reflux overnight. The mixture was concentrated to yield the desired product (310 mg, 66.7%). LCMS calculated for C21H23N8O2(M+H): 419.2; found 419.2.

1. temperaturewas heated
2. temperatureto reflux overnight
3. concentrationThe mixture was concentrated