4-Methoxybenzohydrazide → 4-Methoxy-benzoic acid-(1-imino-propyl)-hydrazide

HRID 1787853Notes

Reaction equation

HRID 1787853 reaction equation
Cl.[C:2](N)(=[NH:5])[CH2:3][CH3:4].[CH3:7][O:8][C:9]1[CH:18]=[CH:17][C:12]([C:13]([NH:15][NH2:16])=[O:14])=[CH:11][CH:10]=1>>[NH:5]=[C:2]([N:15]([C:13](=[O:14])[C:12]1[CH:11]=[CH:10][C:9]([O:8][CH3:7])=[CH:18][CH:17]=1)[NH2:16])[CH2:3][CH3:4]

Participants

3

Reactant 2

HCID 767924-MethoxybenzohydrazideHCID 12301253Propionimidamide hydrochloride

Product 1

HCID 684954834-Methoxy-benzoic acid-(1-imino-propyl)-hydrazide

Procedure

Prepared from 4.90 g (45 mmol) of propioamidine hydrochloride and 5.00 g (30 mmol) of 4-methoxy-benzoic acid hydrazide analogously to the method described in P-1-a). After the ethanol has been distilled off 10.0 g of crude product are obtained which are reacted without any further purification.

Workup

  1. distillationAfter the ethanol has been distilled off 10.0 g of crude product
  2. customare obtained which
  3. customare reacted without any further purification

Sources & evidence

ORD record
ord-00c1178714e54103bd2c468d0d4bb1bd
Source dataset
uspto-grants-2009_03
Patent number
US07511067B2

Reaction notes

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