HCID 59754200, compound → HCID 57602520, compound

HRID 1787855Notes

Reaction equation

HRID 1787855 reaction equation
C([O:8][C:9]1[CH:18]=[CH:17][C:16]([C:19](=[O:25])[CH:20](OCC)O)=[CH:15][C:10]=1[C:11]([O:13]C)=O)C1C=CC=CC=1.[F:26][C:27]1[CH:28]=[C:29]([C:34]2[N:38]=[C:37]([CH3:39])[N:36]([CH2:40][CH2:41][C:42]([NH2:45])([CH3:44])[CH3:43])[N:35]=2)[CH:30]=[C:31]([F:33])[CH:32]=1>>[F:33][C:31]1[CH:30]=[C:29]([C:34]2[N:38]=[C:37]([CH3:39])[N:36]([CH2:40][CH2:41][C:42]([NH:45][CH2:20][CH:19]([C:16]3[CH:17]=[CH:18][C:9]([OH:8])=[C:10]([CH2:11][OH:13])[CH:15]=3)[OH:25])([CH3:43])[CH3:44])[N:35]=2)[CH:28]=[C:27]([F:26])[CH:32]=1

Participants

3

Reactant 2

HCID 59754200HCID 59754200, compoundHCID 68858509Methyl benzyloxy-5-(2-ethoxy-2-hydroxy-acetyl)-benzoate

Product 1

HCID 57602520HCID 57602520, compound

Procedure

The compound is obtained according to general working method A from 121 mg (0.35 mmol) of methyl 2-benzyloxy-5-(2-ethoxy-2-hydroxy-acetyl)-benzoate and 98 mg (0.35 mmol) of 3-[3-(3,5-difluoro-phenyl)-5-methyl-[1,2,4]triazol-1-yl]-1,1-dimethyl-propylamine. Yield: 9 mg (6%); mass spectroscopy [M+H]+=447.

Workup

  1. customThe compound is obtained

Sources & evidence

ORD record
ord-06dc23e17530430893a7bcabb9eda233
Source dataset
uspto-grants-2009_03
Patent number
US07511067B2

Reaction notes

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