HCID 59754195, compound → HCID 57602522, compound
Reaction equation
C([O:8][C:9]1[CH:18]=[CH:17][C:16]([C:19](=[O:25])[CH:20](OCC)O)=[CH:15][C:10]=1[C:11]([O:13]C)=O)C1C=CC=CC=1.[F:26][C:27]1[CH:32]=[CH:31][C:30]([C:33]2[N:37]=[C:36]([CH3:38])[N:35]([CH2:39][CH2:40][C:41]([NH2:44])([CH3:43])[CH3:42])[N:34]=2)=[CH:29][CH:28]=1>>[F:26][C:27]1[CH:28]=[CH:29][C:30]([C:33]2[N:37]=[C:36]([CH3:38])[N:35]([CH2:39][CH2:40][C:41]([NH:44][CH2:20][CH:19]([C:16]3[CH:17]=[CH:18][C:9]([OH:8])=[C:10]([CH2:11][OH:13])[CH:15]=3)[OH:25])([CH3:42])[CH3:43])[N:34]=2)=[CH:31][CH:32]=1Participants
3
Procedure
Prepared according to general working method A from 344 mg (1 mmol) of methyl 2-benzyloxy-5-(2-ethoxy-2-hydroxy-acetyl)-benzoate and 262 mg (1 mmol) of 3-[3-(4-fluoro-phenyl)-5-methyl-[1,2,4]triazol-1-yl]-1,1-dimethyl-propylamine.
Workup
- customPrepared
Sources & evidence
- ORD record
- ord-e5d952dab2484b08a7aa51cb7c6ebfd4
- Source dataset
- uspto-grants-2009_03
- Patent number
- US07511067B2
Reaction notes
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