HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetate → HCID 68830632, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetate | HCID 84468 | — |
| Reactant | 3-amino-N-(5-chloropyridin-2-yl)pyridine-2-carboxamide | HCID 11557851 | — |
| Reactant | 2-(N-Boc-piperidine-4-yloxy)-4-(tert-butyl)benzoic acid | HCID 68530505 | — |
| Product | HCID 68830632 | HCID 68830632 | 30% |
Reaction Steps
Using methods substantially equivalent to those described in Example 1-I, 3-amino-N-(5-chloropyridin-2-yl)-pyridine-2-carboxamide (626 mg, 2.52 mmol) and 2-(1-tert-butoxycarbonylpiperidin-4-yloxy)-4-tert-butylbenzoic acid (500 mg, 1.47 mmol) yielded, after deprotection of the coupled product using methods substantially equivalent to those described in Example 1-J, 470 mg (30%) of the title compound as a trifluoroacetate salt.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07511066B2 |
| Source dataset | uspto-grants-2009_03 |
| ORD ID | ord-2824e47e2c2d4ebf8986ba5d92c2c82d |
| Source note | uspto-grants-2009_03 |