L-Leucine → HCID 23692487, compound

HRID 1788306Notes

Reaction equation

HRID 1788306 reaction equation
[NH2:1][C@H:2]([C:7]([OH:9])=[O:8])[CH2:3][CH:4]([CH3:6])[CH3:5].[OH-].[K+:11]>O>[NH2:1][CH:2]([CH2:3][CH:4]([CH3:6])[CH3:5])[C:7]([O-:9])=[O:8].[K+:11]

Participants

4

Reactant 2

HCID 6106L-LeucineHCID 14797Potassium Hydroxide

Product 1

HCID 23692487HCID 23692487, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

Separately, in a single-necked, round bottomed flask, equipped with a magnetic stirrer, 7.87 g (60 mmol) of Leucine is dissolved in 300 ml of water. To this is added 72 ml of 1 M potassium hydroxide with vigorous stirring, until heat production ceases. At this point the water is removed by evaporation to yield the carboxylate salt, potassium 2-amino-4-methylpentanoate, shown below.

Workup

  1. customSeparately, in a single-necked, round bottomed flask, equipped with a magnetic stirrer
  2. temperatureuntil heat production ceases
  3. customAt this point the water is removed by evaporation

Sources & evidence

ORD record
ord-345d0a27018043d1a770069557aa1330
Source dataset
uspto-grants-2009_03
Patent number
US07511162B2

Reaction notes

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