HRID1788408

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID5951

(2S)-2-Amino-3-hydroxy-propanoic acid

C3H7NO3

结构：O=C(O)c1ccc2c(c1)nc(-c1ccc3nc(-c4ccccc4)ccc3c1)n2C1CCCCC1

HCID11213026

未命名化合物

PRODUCTS

生成物

结构：O=C(NC(CO)C(=O)O)c1ccc2c(c1)nc(-c1ccc3nc(-c4ccccc4)ccc3c1)n2C1CCCCC1

HCID57623691

未命名化合物

收率 36%

PROCEDURE

实验过程

Compound 231 was synthesized from Compound 201 as described for Compound 235, except L-serine was used instead of L-5-hydroxytryptophane. Yield: 36%.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-b9acaf5e7aee4f5993ef2b0b1bcf0fa7
来源数据集: uspto-grants-2009_03
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07511145B2
来源说明: uspto-grants-2009_03

反应 SMILES

[CH:1]1([N:7]2[C:11]3[CH:12]=[CH:13][C:14]([C:16]([OH:18])=O)=[CH:15][C:10]=3[N:9]=[C:8]2[C:19]2[CH:20]=[C:21]3[C:26](=[CH:27][CH:28]=2)[N:25]=[C:24]([C:29]2[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=2)[CH:23]=[CH:22]3)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[NH2:35][C@H:36]([C:39]([OH:41])=[O:40])[CH2:37][OH:38]>>[CH:1]1([N:7]2[C:11]3[CH:12]=[CH:13][C:14]([C:16]([NH:35][CH:36]([CH2:37][OH:38])[C:39]([OH:41])=[O:40])=[O:18])=[CH:15][C:10]=3[N:9]=[C:8]2[C:19]2[CH:20]=[C:21]3[C:26](=[CH:27][CH:28]=2)[N:25]=[C:24]([C:29]2[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=2)[CH:23]=[CH:22]3)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1