L-Serine → HCID 57623691, compound

HRID 1788408Notes

Reaction equation

HRID 1788408 reaction equation
[CH:1]1([N:7]2[C:11]3[CH:12]=[CH:13][C:14]([C:16]([OH:18])=O)=[CH:15][C:10]=3[N:9]=[C:8]2[C:19]2[CH:20]=[C:21]3[C:26](=[CH:27][CH:28]=2)[N:25]=[C:24]([C:29]2[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=2)[CH:23]=[CH:22]3)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[NH2:35][C@H:36]([C:39]([OH:41])=[O:40])[CH2:37][OH:38]>>[CH:1]1([N:7]2[C:11]3[CH:12]=[CH:13][C:14]([C:16]([NH:35][CH:36]([CH2:37][OH:38])[C:39]([OH:41])=[O:40])=[O:18])=[CH:15][C:10]=3[N:9]=[C:8]2[C:19]2[CH:20]=[C:21]3[C:26](=[CH:27][CH:28]=2)[N:25]=[C:24]([C:29]2[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=2)[CH:23]=[CH:22]3)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1

Participants

3

Reactant 2

HCID 5951L-SerineHCID 11213026HCID 11213026, compound

Product 1

HCID 57623691HCID 57623691, compoundYield 36%

Procedure

Compound 231 was synthesized from Compound 201 as described for Compound 235, except L-serine was used instead of L-5-hydroxytryptophane. Yield: 36%.

Sources & evidence

ORD record
ord-b9acaf5e7aee4f5993ef2b0b1bcf0fa7
Source dataset
uspto-grants-2009_03
Patent number
US07511145B2

Reaction notes

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