HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 6993434, compound → HCID 5276157, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 6993434 | HCID 6993434 | — |
| Reactant | HCID 11213026 | HCID 11213026 | — |
| Reactant | Anisole trifluoroacetic acid | HCID 66633105 | — |
| Product | HCID 5276157 | HCID 5276157 | 15% |
Reaction Steps
Compound 232 was synthesized from Compound 201 as described for Compound 235, except H-Lys(Boc)-OtBu was used instead of L-5-hydroxytryptophane. In the 3rd step the protected intermediate was treated with a mixture of TFA-anisol 8:2 for 2 hours then the product was precipitated with ether and purified on RP-HPLC. Yield 15%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07511145B2 |
| Source dataset | uspto-grants-2009_03 |
| ORD ID | ord-35ed362bf35043f095ba059817691909 |
| Source note | uspto-grants-2009_03 |