HRID1788410

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID145742

L-Proline

C5H9NO2

结构：O=C(O)c1ccc2c(c1)nc(-c1ccc3nc(-c4ccccc4)ccc3c1)n2C1CCCCC1

HCID11213026

未命名化合物

PRODUCTS

生成物

结构：O=C(O)C1CCCN1C(=O)c1ccc2c(c1)nc(-c1ccc3nc(-c4ccccc4)ccc3c1)n2C1CCCCC1

HCID5276158

未命名化合物

收率 15%

PROCEDURE

实验过程

Compound 233 was synthesized from Compound 201 as described for Compound 235, except L-proline was used instead of L-5-hydroxytryptophane. Yield: 15%.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-2fd0395e750240669fd42f7dddee8699
来源数据集: uspto-grants-2009_03
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07511145B2
来源说明: uspto-grants-2009_03

反应 SMILES

[CH:1]1([N:7]2[C:11]3[CH:12]=[CH:13][C:14]([C:16](O)=[O:17])=[CH:15][C:10]=3[N:9]=[C:8]2[C:19]2[CH:20]=[C:21]3[C:26](=[CH:27][CH:28]=2)[N:25]=[C:24]([C:29]2[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=2)[CH:23]=[CH:22]3)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[NH:35]1[CH2:42][CH2:41][CH2:40][C@H:36]1[C:37]([OH:39])=[O:38]>>[CH:1]1([N:7]2[C:11]3[CH:12]=[CH:13][C:14]([C:16]([N:35]4[CH2:42][CH2:41][CH2:40][CH:36]4[C:37]([OH:39])=[O:38])=[O:17])=[CH:15][C:10]=3[N:9]=[C:8]2[C:19]2[CH:20]=[C:21]3[C:26](=[CH:27][CH:28]=2)[N:25]=[C:24]([C:29]2[CH:30]=[CH:31][CH:32]=[CH:33][CH:34]=2)[CH:23]=[CH:22]3)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1