HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Cyclohexyl-2-[[1-cyclohexyl-2-(2-phenylquinoxalin-6-yl)benzimidazole-5-carbonyl]amino]propanoic acid → 2-[[1-Cyclohexyl-2-(2-phenylquinoxalin-6-yl)benzimidazole-5-carbonyl]amino]-4-methyl-pentanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Cyclohexyl-2-[[1-cyclohexyl-2-(2-phenylquinoxalin-6-yl)benzimidazole-5-carbonyl]amino]propanoic acid | HCID 5276167 | — |
| Reactant | 9H-Fluoren-9-ylmethyl N-[(1S)-1-formyl-3-methylbutyl]carbamate | HCID 10042700 | — |
| Product | 2-[[1-Cyclohexyl-2-(2-phenylquinoxalin-6-yl)benzimidazole-5-carbonyl]amino]-4-methyl-pentanoic acid | HCID 5276192 | 14% |
Reaction Steps
The general procedure described for Compound 242 was used with Fmoc-Leu Wang resin (111 mg, 0.9 mmol/g), producing 8.1 mg of the title compound (14% yield). MS: 560.25 (M−H+) HPLC Procedure A, retention time=17.17 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07511145B2 |
| Source dataset | uspto-grants-2009_03 |
| ORD ID | ord-16acc94d2e88466fa25743098ed6bc7b |
| Source note | uspto-grants-2009_03 |