Methyl 4-aminobenzoate → HCID 178498126, compound

HRID 1788434Notes

Reaction equation

HRID 1788434 reaction equation
[CH3:1][O:2][C:3](=[O:11])[C:4]1[CH:9]=[CH:8][C:7]([NH2:10])=[CH:6][CH:5]=1.[Br:12][C:13]1[CH:20]=[CH:19][CH:18]=[CH:17][C:14]=1[CH:15]=O>CO>[CH3:1][O:2][C:3](=[O:11])[C:4]1[CH:9]=[CH:8][C:7](/[N:10]=[CH:15]/[C:14]2[CH:17]=[CH:18][CH:19]=[CH:20][C:13]=2[Br:12])=[CH:6][CH:5]=1

Participants

4

Reactant 2

HCID 12082Methyl 4-aminobenzoateHCID 811292-Bromobenzaldehyde

Product 1

HCID 178498126HCID 178498126, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

4-aminobenzoic acid methyl ester (1.51 g, 10 mmol) and 2-bromobenzaldehyde (1.45 mL, 12.5 mmol) were dissolved in 15 mL of methanol. The mixture was let stand overnight. A white precipitate formed and the crystals were filtered off, washed with cold methanol (2×) and dried.

Workup

  1. customA white precipitate formed
  2. filtrationthe crystals were filtered off
  3. washwashed with cold methanol (2×)
  4. customdried

Sources & evidence

ORD record
ord-4b497d444bf14705a74cc22daed94216
Source dataset
uspto-grants-2009_03
Patent number
US07511145B2

Reaction notes

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