Sulfuric acid magnesium salt (1:1) → HCID 68924573, compound

Participants

Reaction Steps

In 20 mL methanol 100 mg of 10% Pd-C was pre-hydrogenated in the presence of 1 g MgSO4 at 30 psi for 15 minutes. Compound 354c (100 mg) dissolved in a solution of 20 mL of methanol containing 2 mL triethylamine, was added to the catalyst and the hydrogenation was continued for 30 minutes. The catalyst and the magnesium sulfate were filtered using Celite. The solution was evaporated to dryness and the oily residue was used immediately in the following step.

Provenance & Evidence