HRID1788450

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID8651

1,2-Diphenylethanedione

C14H10O2

结构：Nc1ccc(-c2nc3cc(C(=O)O)ccc3n2C2CCCCC2)cc1N

HCID68922299

未命名化合物

PRODUCTS

生成物

结构：O=C(O)c1ccc2c(c1)nc(-c1ccc3nc(-c4ccccc4)c(-c4ccccc4)nc3c1)n2C1CCCCC1

HCID5276027

未命名化合物

PROCEDURE

实验过程

A solution of 100 mg (0.29 mmol) of Compound 406b and 74 mg (0.35 mmol) of benzil was stirred at room temperature overnight. The solvent was evaporated and the residue was purified on preparative HPLC yielding 10 mg.

WORKUP

后处理

customThe solvent was evaporated
customthe residue was purified on preparative HPLC
customyielding 10 mg

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-afe93530b68c4c44afbddeeb0e91daec
来源数据集: uspto-grants-2009_03
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07511145B2
来源说明: uspto-grants-2009_03

反应 SMILES

[CH:1]1([N:7]2[C:11]3[CH:12]=[CH:13][C:14]([C:16]([OH:18])=[O:17])=[CH:15][C:10]=3[N:9]=[C:8]2[C:19]2[CH:24]=[CH:23][C:22]([NH2:25])=[C:21]([NH2:26])[CH:20]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[C:27]1([C:33]([C:35]([C:37]2[CH:42]=[CH:41][CH:40]=[CH:39][CH:38]=2)=O)=O)[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=1>>[CH:1]1([N:7]2[C:11]3[CH:12]=[CH:13][C:14]([C:16]([OH:18])=[O:17])=[CH:15][C:10]=3[N:9]=[C:8]2[C:19]2[CH:20]=[C:21]3[C:22](=[CH:23][CH:24]=2)[N:25]=[C:35]([C:37]2[CH:42]=[CH:41][CH:40]=[CH:39][CH:38]=2)[C:33]([C:27]2[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=2)=[N:26]3)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1