1,2-Bis(4-methylphenyl)-1,2-ethanedione → 2-[2,3-Bis(p-tolyl)quinoxalin-6-yl]-1-cyclohexyl-benzimidazole-5-carboxylic acid
Reaction equation
[CH:1]1([N:7]2[C:11]3[CH:12]=[CH:13][C:14]([C:16]([OH:18])=[O:17])=[CH:15][C:10]=3[N:9]=[C:8]2[C:19]2[CH:20]=[C:21]3[C:26](=[CH:27][CH:28]=2)[N:25]=C(C2C=CC=CC=2)C(C2C=CC=CC=2)=[N:22]3)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[CH3:41][C:42]1[CH:47]=[CH:46][C:45]([C:48]([C:50]([C:52]2[CH:57]=[CH:56][C:55]([CH3:58])=[CH:54][CH:53]=2)=O)=O)=[CH:44][CH:43]=1>>[CH:1]1([N:7]2[C:11]3[CH:12]=[CH:13][C:14]([C:16]([OH:18])=[O:17])=[CH:15][C:10]=3[N:9]=[C:8]2[C:19]2[CH:20]=[C:21]3[C:26](=[CH:27][CH:28]=2)[N:25]=[C:48]([C:45]2[CH:46]=[CH:47][C:42]([CH3:41])=[CH:43][CH:44]=2)[C:50]([C:52]2[CH:57]=[CH:56][C:55]([CH3:58])=[CH:54][CH:53]=2)=[N:22]3)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1Participants
3
Procedure
Prepared as described for Compound 406 using 4,4′-dimethylbenzil in place of benzil.
Workup
- customPrepared
Sources & evidence
- ORD record
- ord-c5ab237a4e2847d4b2dfa35bd3ca34f0
- Source dataset
- uspto-grants-2009_03
- Patent number
- US07511145B2
Reaction notes
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