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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1788461Generated: October 25, 2026

L-Serinamide → 2-[2-(1-Carbamoyl-2-hydroxyethylcarbamoyl)quinolin-6-yl]-1-cyclohexyl-1H-benzimidazole-5-carboxylic Acid

https://huagongshe.com/reaction/1788461

Reaction equation

Participants

RoleNameHCIDCharge
ReactantL-SerinamideHCID 101138—
Reactant2-[2-(1-Carbamoylethylcarbamoyl)quinolin-6-yl]-1-cyclohexyl-1H-benzimidazole-5-carboxylic AcidHCID 57603050—
Reactant2-[2-(1-Carbamoylethylcarbamoyl)quinolin-6-yl]-1-cyclohexyl-1H-benzimidazole-5-carboxylic Acid Ethyl EsterHCID 68919557—
Product2-[2-(1-Carbamoyl-2-hydroxyethylcarbamoyl)quinolin-6-yl]-1-cyclohexyl-1H-benzimidazole-5-carboxylic AcidHCID 6915826—

Reaction Steps

The title compound (5 mg yield) was prepared as described for Compound 497a using L-serinamide in place of L-alaninamide and hydrolyzed as described for Compound 497.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07511145B2
Source datasetuspto-grants-2009_03
ORD IDord-e94738fce59f4a0a8f2a34c090dfa959
Source noteuspto-grants-2009_03