HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromo-5-nitrotoluene → 2-Amino-5-bromobenzaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromo-5-nitrotoluene | HCID 81577 | — |
| Reactant | Methyl 4-amino-3-formylbenzoate | HCID 46911801 | — |
| Product | 2-Amino-5-bromobenzaldehyde | HCID 23510475 | — |
Reaction Steps
The title intermediate was synthesized as described for Compound 7 in five steps starting from 5-bromo-2-nitrotoluene instead of 3-methyl-4-nitrobenazoic acid methyl ester. MS: 199.97 & 201.97 (M+H+); H1-NMR (CDCl3): δ (ppm) 9.75 (s, 1H), 7.71 (s, 1H), 7.39 (d, 1H, J=9.3 Hz), 7.22 (s, 2H), 6.72 (d, 1H, J=9.3 Hz);
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07511145B2 |
| Source dataset | uspto-grants-2009_03 |
| ORD ID | ord-2610541fefbf4ea1800dbbcae7606982 |
| Source note | uspto-grants-2009_03 |