HuagongsheHuagongshe Chemistry Print Report · For research reference only
8-Amino-2-naphthalenol → 1-Cyclohexyl-2-(2-phenyl-quinoxalin-6-yl)-1H-benzoimidazole-5-carboxylic Acid (7-hydroxy-naphthalen-1-yl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 8-Amino-2-naphthalenol | HCID 8358 | — |
| Reactant | 1-cyclohexyl-2-(2-phenyl-quinoxalin-6-yl)-1H-benzoimidazole-5-carboxylic Acid morpholin-4-ylamide | HCID 57603045 | — |
| Product | 1-Cyclohexyl-2-(2-phenyl-quinoxalin-6-yl)-1H-benzoimidazole-5-carboxylic Acid (7-hydroxy-naphthalen-1-yl)-amide | HCID 136096451 | 20% |
Reaction Steps
The general procedure described for Compound 574 was used with 8-amino-naphthalen-2-ol (15.9 mg), producing 5 mg of the title compound (20% yield). MS: 590.25 (M+H+) HPLC Procedure A, retention time=15.31 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07511145B2 |
| Source dataset | uspto-grants-2009_03 |
| ORD ID | ord-f19e1d607e984d218444c87191fc51c7 |
| Source note | uspto-grants-2009_03 |