HRID1788551
反应详情
EQUATION
反应方程式
REACTANTS
反应物
PRODUCTS
生成物
PROCEDURE
实验过程
The amine was reacted with Compound 259e (0.125 g, 0.274 mmol) in the presence of HBTU (0.114 g, 0.30 mmol), followed cyclization in AcOH according to procedures described for the preparation of Compound 477d. Separation by RP HPLC (from 10% of buffer B to 85% of buffer B) gave the title compound (42 mg, 23%).
WORKUP
后处理
- customSeparation by RP HPLC (from 10% of buffer B to 85% of buffer B)