Isopropylamine → 2-[2-[2-(4-Chlorophenyl)-5-methoxy-phenyl]-6-quinolyl]-1-isopropyl-benzimidazole-5-carboxylic acid

HRID 1788557Notes

Reaction equation

HRID 1788557 reaction equation
Cl[C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[CH:4][C:3]=1[N+:11]([O-])=O.C(N)(C)C.[Cl:18][C:19]1[CH:56]=[CH:55][C:22]([C:23]2[C:28]([C:29]3[CH:38]=[CH:37][C:36]4[C:31](=[CH:32][CH:33]=[C:34]([C:39]5N(CC)[C:42]6C=CC(C(O)=O)=[CH:49][C:41]=6[N:40]=5)[CH:35]=4)[N:30]=3)=[CH:27][C:26]([O:53][CH3:54])=[CH:25][CH:24]=2)=[CH:21][CH:20]=1>>[Cl:18][C:19]1[CH:56]=[CH:55][C:22]([C:23]2[C:28]([C:29]3[CH:38]=[CH:37][C:36]4[C:31](=[CH:32][CH:33]=[C:34]([C:39]5[N:40]([CH:41]([CH3:49])[CH3:42])[C:2]6[CH:10]=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[CH:4][C:3]=6[N:11]=5)[CH:35]=4)[N:30]=3)=[CH:27][C:26]([O:53][CH3:54])=[CH:25][CH:24]=2)=[CH:21][CH:20]=1

Participants

4

Procedure

The title compound was prepared from Resin 534a and isopropylamine according to the procedure described in the preparation of Compound 534.

Sources & evidence

ORD record
ord-4a1059e9eaba4776a1501cce895e62b3
Source dataset
uspto-grants-2009_03
Patent number
US07511145B2

Reaction notes

Loading…