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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1788561Generated: November 1, 2026

4-Chloro-3-nitrobenzoic acid → 2-[2-[2-(4-Chlorophenyl)-5-methoxy-phenyl]-6-quinolyl]-1-(1-ethylpropyl)benzimidazole-5-carboxylic acid

https://huagongshe.com/reaction/1788561

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Chloro-3-nitrobenzoic acidHCID 7320—
Reactant3-PentanamineHCID 12019—
Reactant2-[2-[2-(4-Chlorophenyl)-5-methoxy-phenyl]-6-quinolyl]-1-ethyl-benzimidazole-5-carboxylic acidHCID 5276184—
Product2-[2-[2-(4-Chlorophenyl)-5-methoxy-phenyl]-6-quinolyl]-1-(1-ethylpropyl)benzimidazole-5-carboxylic acidHCID 5276149—

Reaction Steps

The title compound was prepared from Resin 534a and 1-ethylpropylamine according to the procedure described in the preparation of Compound 534.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07511145B2
Source datasetuspto-grants-2009_03
ORD IDord-252469d1f4154aa39e4f99d256124b0c
Source noteuspto-grants-2009_03