4-Chloro-3-nitrobenzoic acid → HCID 5276141, compound

HRID 1788567Notes

Reaction equation

HRID 1788567 reaction equation
ClC1C=CC(C(O)=O)=CC=1[N+]([O-])=O.[CH3:14][C:15]1([CH3:23])[CH2:20][CH:19]([CH3:21])[CH2:18][CH:17]([NH2:22])[CH2:16]1.[Cl:24][C:25]1[CH:62]=[CH:61][C:28]([C:29]2[C:34]([C:35]3[CH:44]=[CH:43][C:42]4[C:37](=[CH:38][CH:39]=[C:40]([C:45]5N(CC)[C:48]6[CH:52]=[CH:53][C:54]([C:56]([OH:58])=[O:57])=[CH:55][C:47]=6[N:46]=5)[CH:41]=4)[N:36]=3)=[CH:33][C:32]([O:59][CH3:60])=[CH:31][CH:30]=2)=[CH:27][CH:26]=1>>[Cl:24][C:25]1[CH:26]=[CH:27][C:28]([C:29]2[C:34]([C:35]3[CH:44]=[CH:43][C:42]4[C:37](=[CH:38][CH:39]=[C:40]([C:45]5[N:22]([CH:17]6[CH2:18][CH:19]([CH3:21])[CH2:20][C:15]([CH3:23])([CH3:14])[CH2:16]6)[C:48]6[CH:52]=[CH:53][C:54]([C:56]([OH:58])=[O:57])=[CH:55][C:47]=6[N:46]=5)[CH:41]=4)[N:36]=3)=[CH:33][C:32]([O:59][CH3:60])=[CH:31][CH:30]=2)=[CH:61][CH:62]=1

Participants

4

Reactant 3

HCID 73204-Chloro-3-nitrobenzoic acidHCID 85931Cyclohexanamine, 3,3,5-trimethyl-HCID 52761842-[2-[2-(4-Chlorophenyl)-5-methoxy-phenyl]-6-quinolyl]-1-ethyl-benzimidazole-5-carboxylic acid

Product 1

HCID 5276141HCID 5276141, compound

Procedure

The title compound was prepared from Resin 534a and 3,3,5-trimethylcyclohexylamine according to the procedure described in the preparation of Compound 534.

Sources & evidence

ORD record
ord-4dda83994225470db26d050c1f5260e3
Source dataset
uspto-grants-2009_03
Patent number
US07511145B2

Reaction notes

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