HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Acetophenone → 2-[2-(2-Bromophenyl)-6-quinolyl]-1-cyclohexyl-benzimidazole-5-carboxylic acid
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Acetophenone | HCID 7410 | — |
| Edukt | 2'-Bromoacetophenone | HCID 75060 | — |
| Edukt | 2-{2-[4'-Chloro-4-(pyrrolidine-1-carbonyl)-biphen-2-yl]-quinolin-6-yl}-1-cyclohexyl-1H-benzoimidazole-5-carboxylic acid | HCID 11181341 | — |
| Edukt | 3-({2-[4'-Chloro-4-(pyrrolidine-1-carbonyl)-biphen-2-yl]-quinoline-6-carbonyl}-amino)-4-cyclohexylamino-benzoic acid ethyl ester | HCID 57603089 | — |
| Produkt | 2-[2-(2-Bromophenyl)-6-quinolyl]-1-cyclohexyl-benzimidazole-5-carboxylic acid | HCID 5275978 | — |
Reaktionsschritte
The title compound was synthesized in four steps as described for Compound 13, Compound 25, Compound 27 Q=ethyl and Compound 204, respectively, except 2′-bromoacetophenon was used in the first step instead of acetophenone.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07511145B2 |
| Quelldatensatz | uspto-grants-2009_03 |
| ORD ID | ord-be5034d2404c402f953fb1dc96bb4aaf |
| Quellennotiz | uspto-grants-2009_03 |