1-Bromohexane → Benzene, 1-bromo-4-(hexyloxy)-

Participants

Reaction Conditions

Reaction Steps

50.0 g (0.290 mol) of p-bromophenyl was dissolved in 300 ml of ethanol and 14.2 g (0.340 mol) of sodium hydroxide and 49.5 g (0.300 mol) of 1-bromohexane were added thereto. The resulting solution was stirred at 70° C. for 4 hours to complete the reaction and the solvent was removed by distillation. Then 150 ml of water was added and the organic layer was extracted with 200 ml of hexane. The hexane was removed by distillation thereafter. The residue was distilled under reduced pressure to yield 63.4 g of 4-hexyloxybromobenzene having a b.p. 139° C./7 mmHg.

Provenance & Evidence