Butylamine → HCID 178449185, compound

Participants

Reaction Steps

A solution of 12.3 g of N-cyano-N'-(1,2,3,4-tetrahydro-1-naphthyl)-S-methylisothiourea and 20 ml of n-butylamine in 100 ml of acetonitrile was heated at reflux with stirring for 100 hours. The solvent was removed by evaporation in vacuo. The residual oil was dissolved in methylene chloride, and the solution was washed with three 80 ml portions of 3N hydrochloric acid and then dried over anhydrous sodium sulfate. The methylene chloride was removed by evaporation in vacuo, leaving as residue N"-cyano-N-n-butyl-N'-(1,2,3,4-tetrahydro-1-naphthyl)guanidine as 9.73 g of a pale yellow, viscous oil.

Provenance & Evidence