4-Ethyl-2,3-dioxopiperazinecarbonyl chloride → HCID 20190187, compound

HRID 1788654Notes

Reaction equation

HRID 1788654 reaction equation
Cl.[NH2:2][CH:3]([C:7]1[N:8]=[N:9][S:10][CH:11]=1)[C:4]([OH:6])=[O:5].[CH2:12]([N:14]1[CH2:19][CH2:18][N:17]([C:20](Cl)=[O:21])[C:16](=[O:23])[C:15]1=[O:24])[CH3:13]>>[CH2:12]([N:14]1[CH2:19][CH2:18][N:17]([C:20]([NH:2][CH:3]([C:7]2[N:8]=[N:9][S:10][CH:11]=2)[C:4]([OH:6])=[O:5])=[O:21])[C:16](=[O:23])[C:15]1=[O:24])[CH3:13]

Participants

3

Reactant 2

HCID 1088134-Ethyl-2,3-dioxopiperazinecarbonyl chlorideHCID 70444564112111-01-0

Product 1

HCID 20190187HCID 20190187, compoundYield 81.3%

Procedure

The title compound (1.24 g) was prepared from 2-amino-2-(1,2,3-thiadiazol-4-yl)acetic acid hydrochloride [Example 3(a)] (912 mg) and 4-ethyl-2,3-dioxopiperazin-1-ylcarbonyl chloride (953 mg) by the method of Example 1(a).

Sources & evidence

ORD record
ord-7117754e6e8640b49cc4ad4fb2f2ff13
Source dataset
uspto-grants-1987_08
Patent number
US04684642

Reaction notes

Loading…