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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 178868Generated: October 25, 2026

Acetic Acid → Tert-butyl 6-azaspiro[2.5]octane-6-carboxylate

https://huagongshe.com/reaction/178868

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetic AcidHCID 176—
ReactantPotassium CationHCID 813—
ReactantHydroxideHCID 961—
ReactantDiethyl EtherHCID 3283—
ReactantTetrahydrofuranHCID 8028—
Reactant1-Boc-4-MethylenepiperidineHCID 2756808—
ReactantN-Methyl-N'-nitro-N-nitrosoguanidineHCID 135436526—
ProductTert-butyl 6-azaspiro[2.5]octane-6-carboxylateHCID 51358341—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-c889d81ebcc54ae282536418769f8f95
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)