反应详情

4 g (0.019 mole) of 2-(1,2,4-triazol-1-ylmethylamino)-4,6-dimethylpyrimidine are suspended in 100 ml of absolute acetonitrile and then 4.3 g (0.019 mole) of 2-chlorophenylsulfonylisocyanate are stirred into the suspension. The batch is stirred for 24 hours at room temperature and the resultant solution is finally concentrated in a rotary evaporator. Crystals of the title compound precipitate and are recrystallized from ethyl acetate, affording 5 g (62% of theory) of the above urea, which melts at 152°-157° C.

1. concentrationthe resultant solution is finally concentrated in a rotary evaporator
2. customCrystals of the title compound precipitate and are recrystallized from ethyl acetate