HCID 13423628, compound → HCID 10332107, compound

Participants

Reaction Steps

49.6 g (0.18 mol) of ethyl 1-(2-nitrobenzyl)-imidazole-2-carboxylate were hydrogenated in 500 ml of tetrahydrofuran at room temperature under a pressure of 5 bar in the presence of Raney nickel. After the theoretical quantity of hydrogen had been absorbed, the catalyst was suction-filtered off, and the filtrate was evaporated. 37.7 g (85.4% of theory) of ethyl 1-(2-aminobenzyl)-imidazol-2-carboxylate, m.p. 104°-106° C. (m.p. from toluene 105°-107° C.) were obtained.

Provenance & Evidence