Water → HCID 54315219, compound

Participants

Reaction Steps

10 g of D-lyxose are dissolved in 120 ml of isopropanol and 60 ml of water and the solution is warmed to 70° C. 18 g of dodecylamine are added. After a clear solution has formed, the temperature is maintained for a further 15 minutes. The mixture is cooled to room temperature and evaporated in vacuo. 10 g of the resulting syrup are dissolved in 100 ml of tetrahydrofuran and 10 ml of methanol, and 10 g of sodium carbonate are added. 5.5 g of dodecanoic acid chloride, dissolved in 20 ml of tetrahydrofuran, are added dropwise at 0° C. When the reaction has ended, the mixture is worked up, and the product purified, as described in Example 2.

Provenance & Evidence