HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Piperazinecarboxylic acid, ethyl ester → HCID 178473356, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Piperazinecarboxylic acid, ethyl ester | HCID 8431 | — |
| Reactant | 2,3-Epoxy-2,3-dihydro-1,4-naphthoquinone | HCID 85844 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 178473356 | HCID 178473356 | 44.9% |
Reaction Steps
A mixture of 1.174 g of 2,3-epoxy-2,3-dihydro-1,4-naphthoquinone, 1.58 g of ethyl-N-piperazinocarboxylate and 100 ml of absolute ethanol was stirred for 24 hours, then evaporated. The residue was chromatographed on silica gel, eluting with 5% methanol in chloroform, giving 1.0 g of the desired product, mp 115°-118° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04686220 |
| Source dataset | uspto-grants-1987_08 |
| ORD ID | ord-befc1a5140b3477ba8bc5c430cf45d86 |
| Source note | uspto-grants-1987_08 |