HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 2,3,4,5-Tetrafluorobenzoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 2,3,4,5-Tetrafluorobenzoic acid | HCID 297549 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2,3,4,5-Tetrafluorobenzoyl chloride | HCID 2733689 | — |
Reaction Steps
Dimethylformamide (0.6 ml) is added to a mixture of 2,3,4,5-tetrafluorobenzoic acid (100 g) and thionyl chloride (135 ml), and the mixture is heated under reflux with stirring for 7 hours. The reaction mixture is condensed under vacuum to yield crude 2,3,4,5-tetrafluorobenzoyl chloride as a pale yellow oily residue (110.5 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04686221 |
| Source dataset | uspto-grants-1987_08 |
| ORD ID | ord-c4d9b52229434296a6515c724df8955a |
| Source note | uspto-grants-1987_08 |