Methyl iodide → HCID 20189343, compound

Participants

Reaction Steps

Methyl iodide (0.06 ml, 0.96 mmoles) was added to a solution of diethyl 2-(aminothioxomethyl)-1,4-dihydro- 6-methyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate (0.2 g, 0.48 mmoles) in methanol (10 ml). After stirring for 16 hours at room temperature methyl iodide (0.1 ml) was added and the stirring continued for 1 day. The solvent was evaporated and the residue crystallised on addition of ether. The hydroscopic solid was filtered and dried in vacuo to give the title compound (0.17 g). Nmr (CDCl3) δ 5.9 (s,H), 2.9 (s,SMe).

Provenance & Evidence