HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → HCID 20189646, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | Mycophenolic Acid | HCID 446541 | — |
| Product | HCID 20189646 | HCID 20189646 | — |
Reaction Steps
A solution of 500 mgs of mycophenolic acid in 10 ml of dichloromethane containing 0.5 ml of thionyl chloride and 0.05 ml of N.N-dimethylformamide was maintained at 25° C. for 3 hours. The volatile components were then distilled off under vacuum to obtain crude (E)-[1,3-dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl]-4-methyl-4-hexenoyl chloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04686234 |
| Source dataset | uspto-grants-1987_08 |
| ORD ID | ord-cf1a75afa44e49b2a2f9d4faab45e775 |
| Source note | uspto-grants-1987_08 |